Serum leptin and adiponectin levels correlate with mast cell activation during exercise-induced bronchospasm in asthmatic children

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Serum leptin and adiponectin levels correlate with mast cell activation during exercise-induced bronchospasm in asthmatic children

Methods Seventy-two prepubertal children from the ages of 6 years to 10 years were recruited in the study. They comprised: asthmatic with EIB (n=24), asthmatic without EIB (n=21), and healthy controls (n=27). We measured exhaled nitric oxide (eNO) and serum eosinophilic cationic protein (ECP), leptin, adiponectin and cytokines. The urinary concentrations of LTE4 and 9a,11b-PGF2 were measured. T...

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Exercise-induced bronchospasm in children.

This review will encompass definition, history, epidemiology, pathogenesis, diagnosis, and management of exercise -induced bronchospasm in the pediatric individual with and without known asthma. Exercise induced asthma is the conventional term for transient airway narrowing in a known asthma in association with strenuous exercise usually lasting 5-10 minutes with a decline in pulmonary function...

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Serum Leptin and Adiponectin Levels in Obese and Nonobese Asthmatic School Children in relation to Asthma Control

There is growing evidence of a positive correlation between asthma and obesity in children and adults. Leptin and adiponectin regulate several metabolic and inflammatory functions. This study aims to evaluate serum leptin and adiponectin concentrations in asthmatic school children to investigate their association with obesity and the degree of asthma control. Obese asthmatic (OA) and nonobese a...

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ژورنال

عنوان ژورنال: World Allergy Organization Journal

سال: 2015

ISSN: 1939-4551

DOI: 10.1186/1939-4551-8-s1-a26